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9th International Workshop on Genotoxicity Testing (IWGT)

Dates: Tue 1 – Fri 4 September 2026

Venue: The John McIntyre Conference Centre, Edinburgh, UK

The success of these workshops is based on our ability to include experts representing regulatory agencies, academia, and industry from across the world.

This workshop is organised as a satellite meeting to the International Conference on Environmental Mutagens (ICEM), held every four years.

REGISTER

Delegate registration: £300

• This workshop is an in-person meeting and registration is for attendance in Edinburgh, UK

The following topics will be addressed at IWGT 2026:

  • Methodological Advances
  • Risk Assessment Innovation
  • Next-Generation Approaches
Methodological Advances

• Liver Micronucleus Assay

Advancing tissue-specific genotoxicity assessment – moving towards an OECD guideline


• Critical Aspects of OECD Technical Guideline 489

Refining standard protocols for enhanced reliability of in vivo Comet assay studies

Providing guidance on how to deal with inconclusive/positive results

Risk Assessment Innovation

• Risk Assessment of Aneugens

Improving evaluation of chromosome-damaging agents


• Statistical Tests for Trend

Strengthening/contextualizing data interpretation methodologies

Next-Generation Approaches

• Quantitative Genotoxicology 2.0

Advancing Quantitative Approaches in Risk Assessment


• Error-Corrected Sequencing (ECS)

Provide expert, referenceable guidance on application of ECS for regulatory purposes


• Strengths and limitations of in silico / QSAR

Formalize use cases and restrictions, bridging towards a potency approach

Steering Committee

• Andreas Zeller (Switzerland, Chair)

• Hans-Jörg Martus (Germany, Co-Chair)

• David Kirkland (UK, Co-Chair)

• Carol Beevers (UK)

• Roland Frötschl (Germany)

• Stephen Dertinger (USA)

• Laura Markley (USA)

• Kiyohiro Hashimoto (Japan)

• Kei-ichi Sugiyama (Japan)

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